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Article

Physical activity and risk of Alzheimer disease: A 2-sample mendelian randomization study.

Neurology - 29 Sept 2020

Baumeister Sebastian E, Karch André, Bahls Martin, Teumer Alexander, Leitzmann Michael F, Baurecht Hansjörg

Abstract excerpt

OBJECTIVE: Evidence from observational studies for the effect of physical activity on the risk of Alzheimer disease (AD) is inconclusive. We performed a 2-sample mendelian randomization analysis to examine whether physical activity is protective for AD. METHODS: Summary data of genome-wide association studies on physical activity and AD were used. The primary study population included 21,982 patients with AD and...

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Identifiers

PMID: 32680943
DOI: 10.1212/WNL.0000000000010013
PMCID: PMC7963349

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