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Article

Physical activity, sedentary behavior and risk of coronary artery disease, myocardial infarction and ischemic stroke: a two-sample Mendelian randomization study.

Clinical research in cardiology : official journal of the German Cardiac Society - 1 Oct 2021

Bahls Martin, Leitzmann Michael F, Karch André, Teumer Alexander, Dörr Marcus, Felix Stephan B, Meisinger Christa, Baumeister Sebastian E, Baurecht Hansjörg

Abstract excerpt

AIMS: Observational evidence suggests that physical activity (PA) is inversely and sedentarism positively related with cardiovascular disease risk. We performed a two-sample Mendelian randomization (MR) analysis to examine whether genetically predicted PA and sedentary behavior are related to coronary artery disease, myocardial infarction, and ischemic stroke. METHODS AND RESULTS: We used single nucleotide...

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Brain Ischemia
Coronary Artery Disease
Exercise
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ischemic Stroke

Mendelian Randomization Analysis

Myocardial Infarction

Sedentary Behavior

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Identifiers

PMID: 33774696
DOI: 10.1007/s00392-021-01846-7
PMCID: PMC8484185

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