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Article

Single-cell transcriptome sequencing of macrophages in common cardiovascular diseases

16 Jan 2023

Abstract excerpt

Macrophages are strategically located throughout the body at key sites in the immune system. A key feature in atherosclerosis is the uptake and accumulation of lipoproteins by arterial macrophages, leading to the formation of foam cells. After myocardial infarction, macrophages derived from monocytes infiltrate the infarcted heart. Macrophages are also closely related to adverse remodeling after heart failure. An...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36822177
DOI: 10.1093/jleuko/qiac014

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