Article
Association between Chronic Obstructive Pulmonary Disease and Exfoliation Syndrome: The Utah Project on Exfoliation Syndrome.
Ophthalmology. Glaucoma - 1 Jan 2000
Taylor Samuel C, Bernhisel Ashlie A, Curtin Karen, Allingham R Rand, Ritch Robert, Wirostko Barbara M
Abstract excerpt
PURPOSE: Exfoliation syndrome (XFS) is associated with genetic variants of lysyl oxidase-like 1 (LOXL1), a key enzyme in the stabilization of extracellular matrix (ECM) and elastin, and in connective tissue repair. Because patients with chronic obstructive pulmonary disease (COPD) have increased and altered elastin degradation, an association between XFS and COPD was hypothesized and analyzed. Impact of XFS on...
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