Article
Risk of atrial fibrillation is increased in patients with exfoliation syndrome: the Utah project on exfoliation syndrome (UPEXS).
Acta ophthalmologica - 1 Jun 2022
Wirostko Barbara M, Curtin Karen, Taylor Samuel C, Paulson Chase, Pompoco Christian, Besch Brian M, Ranjan Ravi, Ritch Robert
Abstract excerpt
PURPOSE: Exfoliation syndrome, a systemic disorder with ocular manifestations, is associated with lysyl oxidase-like gene variants. Along with transforming growth factor beta-1, lysyl oxidase-like 1 is a key enzyme in stabilizing extracellular matrix and remodelling collagen/elastin. Given the role that transforming growth factor beta-1, lysyl oxidase-like gene variants and fibrosis play in atrial fibrillation,...
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