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Article

Molecular Biology of Exfoliation Syndrome.

Journal of glaucoma - 1 Jul 2018

Schlötzer-Schrehardt Ursula

Abstract excerpt

Exfoliation syndrome (XFS) is a common age-related matrix process resulting from excessive production and disordered assembly of elastic microfibrillar components into highly cross-linked fibrillary aggregates throughout the anterior eye segment and various organ systems. The underlying molecular pathophysiology involves a complex interplay of profibrotic protagonists including growth factors, proteolytic enzymes...

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Source

Identifiers

PMID: 29419649
DOI: 10.1097/IJG.0000000000000903

Genes

LOXL1
POMP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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