Genetic association of LOXL1 gene variants and exfoliation glaucoma in a Utah cohort.

doi:10.4161/cc.7.4.5388

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Article

Genetic association of LOXL1 gene variants and exfoliation glaucoma in a Utah cohort.

Cell cycle (Georgetown, Tex.) - 15 Feb 2008

Yang Xian, Zabriskie Norman A, Hau Vincent S, Chen Haoyu, Tong Zongzhong, Gibbs Daniel, Farhi Parisa, Katz Bradley J, Luo Ling, Pearson Erik, Goldsmith Jason, Ma Xiang, Kaminoh Yukki, Chen Yuhong, Yu Baifeng, Zeng Jiexi, Zhang Kang, Yang Zhenglin

Abstract excerpt

Exfoliation glaucoma (XFG) is the commonest identifiable cause of secondary open-angle glaucoma worldwide, characterized by the deposition of fibrillar proteins in the anterior segment of the eye. We investigated LOXL1 gene variants previously identified to confer susceptibility to XFG in a Utah Caucasian cohort. After a standard eye examination protocol we genotyped SNPs rs2165241and rs3825942 in 62 XFG or...

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PMID: 18287813
DOI: 10.4161/cc.7.4.5388

Genes

LOXL1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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