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Article

Emerging roles of oxidative stress in the pathogenesis of pseudoexfoliation syndrome (Review)

28 Jul 2022

Abstract excerpt

Pseudoexfoliation syndrome (PEXS) is a systemic disease caused by defects in the extracellular matrix (ECM) remodelling process leading to the chronic deposition of extracellular, fibrillary, white flaky pseudoexfoliation material (PEXM) throughout the body. Specifically, PEXM deposits on the lens capsule cause open-angle glaucoma, cataracts and blindness in patients with PEXS. Several gene single nucleotide...

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PMID: 35949329
DOI: 10.3892/etm.2022.11539

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