Article
Combined effects of five prothrombotic genotypes and cancer on the risk of a first venous thromboembolic event.
Journal of thrombosis and haemostasis : JTH - 1 Nov 2020
Skille Hanne, Paulsen Benedikte, Hveem Kristian, Gabrielsen Maiken E, Brumpton Ben, Hindberg Kristian, Gran Olga V, Rosendaal Frits R, Braekkan Sigrid K, Hansen John-Bjarne
Abstract excerpt
BACKGROUND: The role of combined prothrombotic genotypes in cancer-related venous thromboembolism (VTE) is scarcely studied. We aimed to investigate the impact of a 5-single nucleotide polymorphism (SNP) score on the risk of VTE in patients with and without cancer using a population-based case-cohort. METHODS: Cases with a first VTE (n = 1493) and a subcohort (n = 13 072) were derived from the Tromsø Study...
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