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Joint Effect of Multiple Prothrombotic Genotypes and Mean Platelet Volume on the Risk of Incident Venous Thromboembolism.

Thrombosis and haemostasis - 1 Nov 2022

Jakobsen Lisa, Frischmuth Tobias, Brækkan Sigrid K, Hansen John-Bjarne, Morelli Vânia M

Abstract excerpt

BACKGROUND: A high mean platelet volume (MPV), a marker of increased platelet reactivity, is a risk factor for venous thromboembolism (VTE). Whether established prothrombotic single nucleotide polymorphisms (SNPs) further increase the VTE risk in subjects with high MPV because of biological interaction remains unknown. AIM: To investigate the joint effect of high MPV and prothrombotic genotypes, comprising a...

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PMID: 35617954
DOI: 10.1055/a-1863-2052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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