Article
Factor V Leiden mutation increases the risk for venous thromboembolism in cancer patients - results from the Vienna Cancer And Thrombosis Study (CATS).
Journal of thrombosis and haemostasis : JTH - 1 Jan 2015
Pabinger I, Ay C, Dunkler D, Thaler J, Reitter E-M, Marosi C, Zielinski C, Mannhalter C
Abstract excerpt
BACKGROUND: Patients with cancer are at an increased risk for venous thromboembolism (VTE). The risk varies markedly in different patient populations. Factor V (FV) Leiden is the most common genetic risk factor for VTE, and the impact of FV Leiden on cancer-associated thrombosis is not yet fully elucidated. OBJECTIVE: To study the impact of FV Leiden on the risk of thrombosis in cancer patients. METHODS: In the...
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