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Article

Polygenic risk scores for prediction of cancer-associated venous thromboembolism in the UK Biobank cohort study

20 Jul 2023

Abstract excerpt

BACKGROUND: Guidelines recommend thromboprophylaxis for patients with cancer at high risk of venous thromboembolism (VTE). Polygenic risk scores may improve VTE prediction but have not yet been evaluated in patients with cancer. OBJECTIVES: We assessed the performance of the 5-, 37-, 297-, extended 297- (additionally including factor V Leiden and prothrombin G20210A), and 100-single-nucleotide polymorphism (SNP)...

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Share to Blood Coagulation and Thrombosis Mechanisms
Share to Blood properties and coagulation
Share to Venous Thromboembolism Diagnosis and Management

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37481074
DOI: 10.1016/j.jtha.2023.07.009

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