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Article

Joint effects of cancer and variants in the factor 5 gene on the risk of venous thromboembolism.

Haematologica - 1 Sept 2016

Gran Olga V, Smith Erin N, Brækkan Sigrid K, Jensvoll Hilde, Solomon Terry, Hindberg Kristian, Wilsgaard Tom, Rosendaal Frits R, Frazer Kelly A, Hansen John-Bjarne

Abstract excerpt

Venous thromboembolism occurs frequently in cancer patients. Two variants in the factor 5 gene (F5), rs6025 encoding for the factor V Leiden mutation R506Q, and rs4524 encoding K858R, have been found to be associated with venous thromboembolism. We assessed the joint effect of active cancer and these two F5 variants on venous thromboembolism risk in a case-cohort study. Cases with a first venous thromboembolism...

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Identifiers

PMID: 27479824
DOI: 10.3324/haematol.2016.147405
PMCID: PMC5060021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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