Article
Predicting venous thrombosis in women using a combination of genetic markers and clinical risk factors.
Journal of thrombosis and haemostasis : JTH - 1 Feb 2015
Bruzelius M, Bottai M, Sabater-Lleal M, Strawbridge R J, Bergendal A, Silveira A, Sundström A, Kieler H, Hamsten A, Odeberg J
Abstract excerpt
BACKGROUND: Family history of venous thromboembolism (VTE) has been suggested to be more useful in risk assessment than thrombophilia testing. OBJECTIVES: We investigated established genetic susceptibility variants for association with VTE and evaluated a genetic risk score in isolation and combined with known trigger factors, including family history of VTE. PATIENTS/METHOD: A total of 18 single nucleotide...
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