Article

Single-cell dissection of a rare human prostate basal cell carcinoma

2019-10-25

Abstract excerpt

As a rare subtype of prostate carcinoma, basal cell carcinoma (BCC) has not been studied extensively and thus lacks systematic molecular characterization. Here we applied single-cell genomic amplification and RNA-Seq to a specimen of human prostate BCC (CK34βE12 + /P63 + /PAP − /PSA − ). The mutational landscape was obtained via whole exome sequencing of the amplification mixture of 49 single cells, and the 5...

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Literature Corpus work: c2094b6f-23e2-5e5d-8f27-1594abe1d809
DOI: 10.1101/818260

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