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Article

Temporal changes in prevalence of molecular markers mediating antimalarial drug resistance in a high malaria transmission setting in Uganda.

The American journal of tropical medicine and hygiene - 1 Jul 2014

Mbogo George W, Nankoberanyi Sheila, Tukwasibwe Stephen, Baliraine Frederick N, Nsobya Samuel L, Conrad Melissa D, Arinaitwe Emmanuel, Kamya Moses, Tappero Jordan, Staedke Sarah G, Dorsey Grant, Greenhouse Bryan, Rosenthal Philip J

Abstract excerpt

Standard therapy for malaria in Uganda changed from chloroquine to chloroquine + sulfadoxine-pyrimethamine in 2000, and artemether-lumefantrine in 2004, although implementation of each change was slow. Plasmodium falciparum genetic polymorphisms are associated with alterations in drug sensitivity. We followed the prevalence of drug resistance-mediating P. falciparum polymorphisms in 982 samples from Tororo, a...

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Identifiers

PMID: 24799371
DOI: 10.4269/ajtmh.13-0647
PMCID: PMC4080569

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Source receipt: pubmed, retrieved 7 Sept 2026.

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