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Prevalence and distribution of Plasmodium falciparum multidrug resistant 1 D1246Y allele among children in Ibadan Southwest, Nigeria

21 Mar 2025

Abstract excerpt

The emergence and spread of the Plasmodium falciparum multidrug-resistant 1 (Pfmdr1) allele pose a significant setback to global efforts to control and eradicate malaria infection by diminishing the efficacy of commonly prescribed antimalarial drugs, particularly in Sub-Saharan Africa, where malaria remains endemic. The Pfmdr1 D1246Y mutation is of specific importance due to its potential role in modulating...

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PMID: 40113916
DOI: 10.1038/s41598-025-94668-w

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