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Article

Diverse Functions of Macrophages in Different Tumor Microenvironments.

Cancer research - 1 Oct 2018

Yang Ming, McKay Daniel, Pollard Jeffrey W, Lewis Claire E

Abstract excerpt

Tumor-associated macrophages are a major constituent of malignant tumors and are known to stimulate key steps in tumor progression. In our review in this journal in 2006, we postulated that functionally distinct subsets of these cells exist in different areas within solid tumors. Here, we review the many experimental and clinical studies conducted since then to investigate the function(s), regulation, and...

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Identifiers

PMID: 30206177
DOI: 10.1158/0008-5472.CAN-18-1367
PMCID: PMC6171744

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Source receipt: pubmed, retrieved 7 Sept 2026.

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