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Article

Tumor-associated macrophages: functional diversity, clinical significance, and open questions.

Seminars in immunopathology - 1 Sept 2013

Biswas Subhra K, Allavena Paola, Mantovani Alberto

Abstract excerpt

Inflammation is now a well-recognized hallmark of cancer progression. Tumor-associated macrophages (TAMs) are one of the major inflammatory cells that infiltrate murine and human tumors. While epidemiological studies indicate a clear correlation between TAM density and poor prognosis in a number of human cancers, transgenic studies and transcriptome profiling of TAMs in mice have established their crucial role in...

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PMID: 23657835
DOI: 10.1007/s00281-013-0367-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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