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Identification of Somatic Mutations in Thirty-year-old Serum Cell-free DNA From Patients With Breast Cancer: A Feasibility Study.

Clinical breast cancer - 1 Oct 2020

Ritter Mathilde, Paradiso Viola, Widmer Patrik, Garofoli Andrea, Quagliata Luca, Eppenberger-Castori Serenella, Soysal Savas D, Muenst Simone, Ng Charlotte K Y, Piscuoglio Salvatore, Weber Walter, Weber Walter P

Abstract excerpt

INTRODUCTION: The aim of this study was to assess the feasibility of cell-free DNA (cfDNA) extraction and circulating tumor DNA sequencing in 30-year-old serum samples. MATERIALS AND METHODS: We evaluated serum samples from 52 patients with breast cancer, which were collected between 1983 and 1991, with correlating clinicopathologic data. cfDNA was extracted by using the QIAamp Circulating Nucleic Acid Extraction...

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PMID: 32650988
DOI: 10.1016/j.clbc.2020.04.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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