Article
Extracellular Vesicle DNA Extraction and Sequencing in Ancient Serum Samples From Patients With Breast Cancer.
Anticancer research - 1 Jul 2024
Heidinger Martin, Egle Daniel, Piscuoglio Salvatore, Navarro-Aguadero Miguel Ángel, Sánchez Sara, Hergueta-Redondo Marta, Gallardo Miguel, Barrio Santiago, García-Peláez Beatriz, Molina-Vila Miguel Angel, Maggi Nadia, Eller Ruth Stefanie, Loesch Julie Marie, Alborelli Ilaria, Peinado Hector, Weber Walter, Weber Walter Paul
Abstract excerpt
BACKGROUND/AIM: Extracellular vesicle DNA (EV-DNA) has emerged as a novel biomarker for tumor mutation detection using liquid biopsies, exhibiting biological advantages compared to cell-free DNA (cfDNA). This study assessed the feasibility of EV-DNA and cfDNA extraction and sequencing in old serum samples of patients with breast cancer (BC). PATIENTS AND METHODS: A total of 28 serum samples of 27 patients with...
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