Article
Use of cell free DNA in breast oncology.
Biochimica et biophysica acta - 1 Apr 2016
Canzoniero Jenna VanLiere, Park Ben Ho
Abstract excerpt
Cell free DNA (cfDNA) are short fragments of nucleic acids present in circulation outside of cells. In patients with cancer, some portion of cfDNA is derived from tumor cells, termed circulating tumor DNA (ctDNA), and contains the same mutations and genetic changes as the cancer. The development of new, more effective methods to detect these changes has led to increased interest in developing ctDNA as a biomarker...
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