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Article

The role of ctDNA detection and the potential of the liquid biopsy for breast cancer monitoring.

Expert review of molecular diagnostics - 1 Jul 2016

Openshaw Mark Robert, Page Karen, Fernandez-Garcia Daniel, Guttery David, Shaw Jacqueline Amanda

Abstract excerpt

INTRODUCTION: Recent advances in deep amplicon sequencing have enabled rapid assessment of somatic mutations and structural changes in multiple cancer genes in DNA isolated from tumour tissues and circulating cell-free DNA (cfDNA). This cfDNA is under investigation as a 'liquid biopsy' for the real time monitoring of patients with cancer in a growing number of research studies and clinical trials. AREAS COVERED:...

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Identifiers

PMID: 27144417
DOI: 10.1080/14737159.2016.1184974

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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