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Article

Inhibition of the ATP synthase sensitizes Staphylococcus aureus towards human antimicrobial peptides.

Scientific reports - 9 Jul 2020

Liu Liping, Beck Christian, Nøhr-Meldgaard Katrine, Peschel Andreas, Kretschmer Dorothee, Ingmer Hanne, Vestergaard Martin

Abstract excerpt

Antimicrobial peptides (AMPs) are an important part of the human innate immune system for protection against bacterial infections, however the AMPs display varying degrees of activity against Staphylococcus aureus. Previously, we showed that inactivation of the ATP synthase sensitizes S. aureus towards the AMP antibiotic class of polymyxins. Here we wondered if the ATP synthase similarly is needed for tolerance...

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Identifiers

PMID: 32647350
DOI: 10.1038/s41598-020-68146-4
PMCID: PMC7347559

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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