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Clemastine Inhibits the Biofilm and Hemolytic of Staphylococcus aureus through the GdpP Protein

2 Mar 2022

Abstract excerpt

The biofilm formation, which protects bacteria from stresses, including antibiotics and host immune responses, can be commonly found in clinical S. aureus isolates worldwide. Treatment failure of traditional antibiotics in biofilm-associated S. aureus infections remains a serious challenge. The novel anti-biofilm drug is urgently needed to address the looming crisis. In this study, clemastine, which is a...

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PMID: 35234502
DOI: 10.1128/spectrum.00541-21

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