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Article

Inhibition of the ATP Synthase Eliminates the Intrinsic Resistance of Staphylococcus aureus towards Polymyxins.

mBio - 5 Sept 2017

Vestergaard Martin, Nøhr-Meldgaard Katrine, Bojer Martin Saxtorph, Krogsgård Nielsen Christina, Meyer Rikke Louise, Slavetinsky Christoph, Peschel Andreas, Ingmer Hanne

Abstract excerpt

Staphylococcus aureus is intrinsically resistant to polymyxins (polymyxin B and colistin), an important class of cationic antimicrobial peptides used in treatment of Gram-negative bacterial infections. To understand the mechanisms underlying intrinsic polymyxin resistance in S. aureus, we screened the Nebraska Transposon Mutant Library established in S. aureus strain JE2 for increased susceptibility to polymyxin...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 28874470
DOI: 10.1128/mBio.01114-17
PMCID: PMC5587909

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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