Article
Risk of Nasopharyngeal Carcinoma Associated with Single Nucleotide Polymorphisms in the MicroRNA Binding Site of SGK3.
Genetic testing and molecular biomarkers - 1 Aug 2020
Zheng Huizhen, Wu Liping, Wang Xiaodan, Chen Qin
Abstract excerpt
Objective: Serum/glucocorticoid regulated kinase is a serine/threonine kinase that is involved in regulating cell proliferation, apoptosis, the cell cycle, and ion channel function. The aim of this study was to analyze the relationship between single nucleotide polymorphisms (SNPs) in the microRNA (miRNA) binding site of the SGK3 gene and the risk of nasopharyngeal carcinoma (NPC). Methods: Three SGK3 loci,...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Asian People
- Binding Sites
- Cell Proliferation
- China
- Female
- Gene Expression Regulation, Neoplastic
- Gene Frequency
