Article
Polymorphism in mature microRNA-608 sequence is associated with an increased risk of nasopharyngeal carcinoma.
Gene - 10 Jul 2015
Qiu Fuman, Yang Lei, Zhang Lisha, Yang Xiaorong, Yang Rongrong, Fang Wenxiang, Wu Di, Chen Jiansong, Xie Chenli, Huang Dongsheng, Zhou Yifeng, Lu Jiachun
Abstract excerpt
Accumulative evidences indicated that microRNAs (miRNAs) can function as tumor suppressors and oncogenes, in which genetic variations are implicated in various cancer susceptibilities. However, it remains unclear whether single nucleotide polymorphisms (SNPs) in mature miRNA sequence alter nasopharyngeal carcinoma (NPC) susceptibility. In this study, we analyzed associations between eight SNPs in miRNA mature...
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