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Article

SGK1 in Human Cancer: Emerging Roles and Mechanisms

19 Jan 2021

Abstract excerpt

Serum and glucocorticoid-induced protein kinase 1 (SGK1) is a member of the "AGC" subfamily of protein kinases, which shares structural and functional similarities with the AKT family of kinases and displays serine/threonine kinase activity. Aberrant expression of SGK1 has profound cellular consequences and is closely correlated with human cancer. SGK1 is considered a canonical factor affecting the expression and...

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PMID: 33542904
DOI: 10.3389/fonc.2020.608722

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