Article
SOAPTyping: an open-source and cross-platform tool for sequence-based typing for HLA class I and II alleles.
BMC bioinformatics - 8 Jul 2020
Zhang Yong, Chen Yongsheng, Xu Huixin, Fang Junbin, Zhao Zijian, Hu Weipeng, Yang Xiaoqin, Ye Jia, Cheng Yun, Wang Jiayin, Sun Weiqiang, Wang Jian, Yang Huanming, Yan Jing, Fang Lin
Abstract excerpt
BACKGROUND: The human leukocyte antigen (HLA) gene family plays a key role in the immune response and thus is crucial in many biomedical and clinical settings. Utilizing Sanger sequencing, the golden standard technology for HLA typing enables accurate identification of HLA alleles in high-resolution. However, only the commercial software, such as uTYPE, SBT-Assign, and SBTEngine, and very few open-source tools...
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