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Article

Toward Individualized Therapy in Acute Myeloid Leukemia: A Contemporary Review.

JAMA oncology - 1 Sept 2015

Kadia Tapan M, Ravandi Farhad, Cortes Jorge, Kantarjian Hagop

Abstract excerpt

Acute myeloid leukemia (AML) is a heterogeneous disease in its clinical presentation, response to therapy, and overall prognosis. For decades, pretreatment karyotype evaluation has served to identify subgroups for risk-adapted postremission therapy, but the initial treatment approach has been largely unchanged. With continued advances in the genetic and epigenetic characterization of AML, we have discovered even...

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Identifiers

PMID: 26181162
DOI: 10.1001/jamaoncol.2015.0617

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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