Article
Spectrum of gene mutations identified by targeted next-generation sequencing in Chinese leukemia patients.
Molecular genetics & genomic medicine - 1 Sept 2020
Yao Hongxia, Wu Congming, Chen Yueqing, Guo Li, Chen Wenting, Pan Yanping, Fu Xiangjun, Wang Guyun, Ding Yipeng
Abstract excerpt
BACKGROUND: Despite targeted sequencing have identified several mutations for leukemia, there is still a limit of mutation screening for Chinese leukemia. Here, we used targeted next-generation sequencing for testing the mutation patterns of Chinese leukemia patients. METHODS: We performed targeted sequencing of 504 tumor-related genes in 109 leukemia samples to identify single-nucleotide variants (SNVs) and...
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