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Article

The impact of SAMHD1 expression and mutation status in mantle cell lymphoma: An analysis of the MCL Younger and Elderly trial.

International journal of cancer - 1 Jan 2021

Roider Tobias, Wang Xi, Hüttl Katrin, Müller-Tidow Carsten, Klapper Wolfram, Rosenwald Andreas, Stewart James Peter, de Castro David Gonzalez, Dreger Peter, Hermine Olivier, Kluin-Nelemans Hanneke C, Grabe Niels, Dreyling Martin, Pott Christiane, Ott German, Hoster Eva, Dietrich Sascha

Abstract excerpt

The sterile alpha motif and histidine-aspartic domain-containing protein 1 (SAMHD1) has been demonstrated to predict the response to high-dose cytarabine consolidation treatment in acute myeloid leukemia patients. Here, we evaluated SAMHD1 as potential biomarker for the response to high-dose cytarabine in mantle cell lymphoma (MCL) patients. We quantified SAMHD1 protein expression and determined the mutation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32638373
DOI: 10.1002/ijc.33202

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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