Article
Conserved Oligomeric Golgi (COG) Complex Proteins Facilitate Orthopoxvirus Entry, Fusion and Spread.
Viruses - 30 Jun 2020
Realegeno Susan, Priyamvada Lalita, Kumar Amrita, Blackburn Jessica B, Hartloge Claire, Puschnik Andreas S, Sambhara Suryaprakash, Olson Victoria A, Carette Jan E, Lupashin Vladimir, Satheshkumar Panayampalli Subbian
Abstract excerpt
Although orthopoxviruses (OPXV) are known to encode a majority of the genes required for replication in host cells, genome-wide genetic screens have revealed that several host pathways are indispensable for OPXV infection. Through a haploid genetic screen, we previously identified several host genes required for monkeypox virus (MPXV) infection, including the individual genes that form the conserved oligomeric...
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