Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparative analyses of the Conserved Oligomeric Golgi (COG) complex in vertebrates

1 Jan 2010

Abstract excerpt

BACKGROUND: The Conserved Oligomeric Golgi (COG) complex is an eight-subunit assembly that localizes peripherally to Golgi membranes and is involved in retrograde vesicular trafficking. COG subunits are organized in two heterotrimeric groups, Cog2, -3, -4 and Cog5, -6, -7, linked by a dimeric group formed by Cog1 and Cog8. Dysfunction of COG complex in humans has been associated with new forms of Congenital...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Cellular transport and secretion
Share to Genetic Syndromes and Imprinting

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20633274
DOI: 10.1186/1471-2148-10-212

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparative analyses of the Conserved Oligomeric Golgi (COG) complex in vertebratesPMID 20633274Read ↗

COG Complex in Golgi Trafficking and Glycosylation.Semantic proximity Read ↗

Deficiencies in subunits of the Conserved Oligomeric Golgi (COG) complex define a novel group of Congenital Disorders of Glycosylation.Semantic proximity Read ↗

Deficiency in COG5 causes a moderate form of congenital disorders of glycosylation.Semantic proximity Read ↗

Deficiency of the Cog8 subunit in normal and CDG-derived cells impairs the assembly of the COG and Golgi SNARE complexes.Semantic proximity Read ↗

Genetic analysis of the subunit organization and function of the conserved oligomeric golgi (COG) complex: studies of COG5- and COG7-deficient mammalian cells.Semantic proximity Read ↗

Golgi inCOGnito: From vesicle tethering to human disease.Semantic proximity Read ↗

Structural basis for a human glycosylation disorder caused by mutation of the COG4 gene.Semantic proximity Read ↗

Golgi function and dysfunction in the first COG4-deficient CDG type II patientSemantic proximity Read ↗

Mutations in COG2 encoding a subunit of the conserved oligomeric golgi complex cause a congenital disorder of glycosylation.Semantic proximity Read ↗

Hypothesis: lobe A (COG1-4)-CDG causes a more severe phenotype than lobe B (COG5-8)-CDG.Semantic proximity Read ↗

Effect of the c.2324C>T Mutation in the COG5 Subunit Gene of the Oligomeric Golgi Complex on Its ExpressionSemantic proximity Read ↗

COG5-CDG: expanding the clinical spectrum.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.