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Article

COG Complex in Golgi Trafficking and Glycosylation.

Sub-cellular biochemistry - 1 Jan 2026

Sumya Farhana Taher, Lupashin Vladimir V

Abstract excerpt

The Conserved Oligomeric Golgi (COG) complex, an evolutionary conserved octameric vesicular tether, is essential for maintaining Golgi function by ensuring accurate delivery of resident proteins to their specific locations. Mutations in human COG subunits result in severe multi-systemic diseases known as COG-Congenital Disorders of Glycosylation (COG-CDG). This review explores the current knowledge of COG complex...

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Identifiers

PMID: 41718976
DOI: 10.1007/978-3-032-16833-7_7
PMCID: PMC13451166

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