Article
The COG and COPI complexes interact to control the abundance of GEARs, a subset of Golgi integral membrane proteins.
Molecular biology of the cell - 1 May 2004
Oka Toshihiko, Ungar Daniel, Hughson Frederick M, Krieger Monty
Abstract excerpt
The conserved oligomeric Golgi (COG) complex is a soluble hetero-octamer associated with the cytoplasmic surface of the Golgi. Mammalian somatic cell mutants lacking the Cog1 (ldlB) or Cog2 (ldlC) subunits exhibit pleiotropic defects in Golgi-associated glycoprotein and glycolipid processing that suggest COG is involved in the localization, transport, and/or function of multiple Golgi processing proteins. We have...
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