GSTP1 c.313A>G, XPD c.934G>A, XPF c.2505T>C and CASP9 c.-1339A>G Polymorphisms and Severity of Vomiting in Head and Neck Cancer Patients treated with Cisplatin Chemoradiation.

doi:10.1111/bcpt.12842

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GSTP1 c.313A>G, XPD c.934G>A, XPF c.2505T>C and CASP9 c.-1339A>G Polymorphisms and Severity of Vomiting in Head and Neck Cancer Patients treated with Cisplatin Chemoradiation.

Basic & clinical pharmacology & toxicology - 1 Dec 2017

Carron Juliana, Lopes-Aguiar Leisa, Costa Ericka Francislaine Dias, Nogueira Guilherme Augusto Silva, Lima Tathiane Regine Penna, Pincinato Eder Carvalho, Visacri Marilia Berlofa, Quintanilha Júlia Coelho França, Moriel Patrícia, Lourenço Gustavo Jacob, Lima Carmen Silvia Passos

Abstract excerpt

Cisplatin (CDDP) chemotherapy associated with radiation (RT) has been used in advanced head and neck squamous cell carcinoma (HNSCC) patients, and vomiting is a common side effect during treatment. This prospective study aimed to identify the roles of GSTM1 and GSTT1 (presents or nulls), GSTP1 c.313A>G, XPC c.2815A>C, XPD c.934G>A and c.2251A>C, XPF c.2505T>C, ERCC1 c.354C>T, MLH1 c.-93G>A, MSH2 c.211 + 9C>G,...

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Identifiers

PMID: 28686330
DOI: 10.1111/bcpt.12842

Genes

CASP9
GSTP1
CASP3
CASP8
ERCC1
EXO1
FAS
GSTM1
GSTT1
MLH1
MSH2
MSH3
XPC

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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