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Article

Susceptibility to oral cancers with CD95 and CD95L promoter SNPs may vary with the site and gender.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Sept 2015

Daripally Sarika, Nallapalle Sateesh Reddy, Katta Saritha, Prasad Vidudala V T S

Abstract excerpt

We investigated risk association of oral cancers (tongue and buccal mucosa cancers) with FAS (-1377G > A and FAS -670 A > G) and FASL (-844 T > C) SNPs, in males and females. A case-control study of 535 oral cancer and 525 control subjects was performed. SNPs were detected in the genomic DNA isolated from peripheral blood using PCR-RFLP. We report FASL -844 T > C SNPs increased risk for buccal mucosa cancer in...

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PMID: 25944167
DOI: 10.1007/s13277-015-3516-x

Genes

FAS

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