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Article

Familial risk for depressive and anxiety disorders: associations with genetic, clinical, and psychosocial vulnerabilities.

Psychological medicine - 1 Mar 2022

van Sprang Eleonore D, Maciejewski Dominique F, Milaneschi Yuri, Elzinga Bernet M, Beekman Aartjan T F, Hartman Catharina A, van Hemert Albert M, Penninx Brenda W J H

Abstract excerpt

BACKGROUND: In research and clinical practice, familial risk for depression and anxiety is often constructed as a simple Yes/No dichotomous family history (FH) indicator. However, this measure may not fully capture the liability to these conditions. This study investigated whether a continuous familial loading score (FLS), incorporating family- and disorder-specific characteristics (e.g. family size, prevalence...

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Source

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Identifiers

PMID: 32624018
DOI: 10.1017/S0033291720002299
PMCID: PMC8961330

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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