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Correlation Between BCL2 and Mcl1 Single Nucleotide Polymorphisms and Chemotherapy Response in Jordanian Patients with Colorectal Cancer.

Current pharmaceutical biotechnology - 1 Jan 2021

Mhaidat Nizar M, Amawi Haneen, Alzoubi Karem H

Abstract excerpt

BACKGROUND: Colorectal cancer is one of the most common types of cancer worldwide and a leading cause of death in Jordan. BCL-2 and MCL-1 are anti-apoptotic proteins that inhibit programmed cell death and their over-expression has been shown to be associated with reduced sensitivity to chemotherapy and poor survival in cancer patients. OBJECTIVES: In the present study, three SNPs in the promoter region of...

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PMID: 32619164
DOI: 10.2174/1389201021666200703200126

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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