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Genetic polymorphisms in FABP2, CYP2E1, and TP53 genes are potentially associated with colorectal cancer susceptibility.

Scientific reports - 3 Sept 2024

Ijaz Maryam, Chen Chien-Chin, Iqbal Rana Khalid, Farooq Hafiza Aneela, Mehmood Rubaida, Asif Muhammad, Akbar Atif, Khan Adil, Ijaz Waseem, Said Mourad Ben, Wondmie Gezahign Fentahun, Ibenmoussa Samir, Okla Mohammad K, Iqbal Furhan

Abstract excerpt

Colorectal cancer (CRC) is among the most prevalent cancers with a high mortality rate. Both genetic and environmental factors contribute to CRC development. This study aimed to assess the association of single nucleotide polymorphisms (SNPs) in the fatty acid binding protein-2 (rs1799883), Cytochrome P450 2E1 (rs3813865), TP53 (rs1042522), and Murine double minute 2 (rs1042522) genes with CRC. A cross-sectional...

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Identifiers

PMID: 39242607
DOI: 10.1038/s41598-024-70381-y
PMCID: PMC11379967

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