Article
KCNB1 gene polymorphisms and related indel as predictor biomarkers of treatment response for colorectal cancer - toward a personalized medicine.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2020
Barbirou Mouadh, Sghaier Ikram, Bedoui Sinda, Ben Abderrazek Rahma, Kraiem Hazar, Farah Azer, Hassiki Rym, Mokrani Amina, Mezlini Amel, Almawi Wassim Y, Loueslati-Yacoubi Besma, Bouhaouala-Zahar Balkiss
Abstract excerpt
The KCNB1 gene variants were differentially associated with cancers. However, their association with colorectal cancer has not yet been explored. We investigated the contribution of the KCNB1 gene variants rs3331, rs1051295, and indel (insertion/deletion) rs11468831 Polymorphism as predictors of the treatment response in colorectal cancer patients. A retrospective study, which involved 291 Tunisian colorectal...
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