Article
The Circulating Nucleic Acid Characteristics of Non-Metastatic Soft Tissue Sarcoma Patients.
International journal of molecular sciences - 24 Jun 2020
Eastley Nicholas, Sommer Aurore, Ottolini Barbara, Neumann Rita, Luo Jin-Li, Hastings Robert K, McCulloch Thomas, Esler Claire P, Shaw Jacqueline A, Ashford Robert U, Royle Nicola J
Abstract excerpt
Soft tissue sarcomas (STS) are rare, malignant tumours with a generally poor prognosis. Our aim was to explore the potential of cell free DNA (cfDNA) and circulating tumour DNA (ctDNA) analysis to track non-metastatic STS patients undergoing attempted curative treatment. The analysed cohort (n = 29) contained multiple STS subtypes including myxofibrosarcomas, undifferentiated pleomorphic sarcomas,...
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