Article

Molecular biomarkers impact survival after neoadjuvant chemoradiation in locally advanced soft tissue sarcoma patients

2026-04-08

Abstract excerpt

<title>Abstract</title> <p> Background Locally advanced, marginally resectable soft tissue sarcomas (STS) are frequently treated with multimodal neoadjuvant strategies to enable limb-sparing, R0 resection. However, pathological response (PR) to neoadjuvant chemoradiation is heterogeneous, and robust molecular predictors of response are lacking. We performed comprehensive DNA/RNA profiling to identify genomic co...

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Literature Corpus work: 291c10f6-36f2-5d51-9bbd-fbb8fba5b2c0
DOI: 10.21203/rs.3.rs-8725409/v1

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