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Article

A QTL on Chr 5 modifies hearing loss associated with the fascin-2 variant of DBA/2J mice.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 2015

Johnson Kenneth R, Longo-Guess Chantal M, Gagnon Leona H

Abstract excerpt

Inbred mouse strains serve as important models for human presbycusis or age-related hearing loss. We previously mapped a locus (ahl8) contributing to the progressive hearing loss of DBA/2J (D2) mice and later showed that a missense variant of the Fscn2 gene, unique to the D2 inbred strain, was responsible for the ahl8 effect. Although ahl8 can explain much of the hearing loss difference between C57BL/6J (B6) and...

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Source

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Identifiers

PMID: 26092689
DOI: 10.1007/s00335-015-9574-y
PMCID: PMC4629822

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ABR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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