Genetics of age-related hearing loss in mice. IV. Cochlear pathology and hearing loss in 25 BXD recombinant inbred mouse strains.

doi:10.1016/s0378-5955(98)00029-x

Back to search

Article

Genetics of age-related hearing loss in mice. IV. Cochlear pathology and hearing loss in 25 BXD recombinant inbred mouse strains.

Hearing research - 1 May 1998

Willott J F, Erway L C

Abstract excerpt

The effects of three putative genes which contribute to age-related hearing loss (AHL genes) were evaluated using auditory brainstem response (ABR) thresholds and post-mortem cochlear histopathology in 25 recombinant BXD inbred mouse strains, originally derived from C57BL/6J (B6) and DBA/2J (D2)...

Topics

Acoustic Stimulation
Age Factors
Animals
Auditory Threshold
Cell Count
Cochlea
Evoked Potentials, Auditory, Brain Stem
Genotype
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Presbycusis
Species Specificity
Spiral Ganglion

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.