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Article

Molecular genetic profiling reveals novel association between FLT3 mutation and survival in glioma.

Journal of neuro-oncology - 1 Jul 2020

Shee Kevin, Chambers Meagan, Hughes Edward G, Almiron Damian A, Deharvengt Sophie J, Green Donald, Lefferts Joel A, Andrew Angeline S, Hickey William F, Tsongalis Gregory J

Abstract excerpt

INTRODUCTION: Recent molecular characterization of gliomas has uncovered somatic gene variation and DNA methylation changes that are associated with etiology, prognosis, and therapeutic response. Here we describe genomic profiling of gliomas assessed for associations between genetic mutations and patient outcomes, including overall survival (OS) and recurrence-free survival (RFS). METHODS: Mutations in a 50-gene...

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PMID: 32583303
DOI: 10.1007/s11060-020-03567-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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