Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network.

doi:10.1200/JCO.2009.23.0805

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Article

Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Dec 2009

Weller Michael, Felsberg Jörg, Hartmann Christian, Berger Hilmar, Steinbach Joachim P, Schramm Johannes, Westphal Manfred, Schackert Gabriele, Simon Matthias, Tonn Jörg C, Heese Oliver, Krex Dietmar, Nikkhah Guido, Pietsch Torsten, Wiestler Otmar, Reifenberger Guido, von Deimling Andreas, Loeffler Markus

Abstract excerpt

PURPOSE: The prognostic value of genetic alterations characteristic of glioblastoma in patients treated according to present standards of care is unclear. PATIENTS AND METHODS: Three hundred one patients with glioblastoma were prospectively recruited between October 2004 and December 2006 at the clinical centers of the German Glioma Network. Two hundred fifty-eight patients had radiotherapy, 199 patients had...

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PMID: 19805672
DOI: 10.1200/JCO.2009.23.0805

Genes

MGMT
IDH1

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