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Article

Analysis of cancer-related mutations in extracellular vesicles RNA by Droplet Digital™ PCR.

BioTechniques - 1 Aug 2020

Yap Soo Ann, Münster-Wandowski Agnieszka, Nonnenmacher Anika, Keilholz Ulrich, Liebs Sandra

Abstract excerpt

Extracellular vesicles (EVs) are taking their place as potential biomarkers in the field of liquid biopsy. In this study, EVs were isolated from plasma samples of 31 patients with colorectal cancer and melanoma via differential centrifugation and Droplet Digital™ PCR (Bio-Rad, CA, USA) was used to profile BRAF V600E/K, KRAS G12A/C/D/V and KRAS G13D mutations from EV-derived cDNA. The concordance rates with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32580578
DOI: 10.2144/btn-2020-0028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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